Menopause & Hormonal Skin Changes / Formula option
Estro-Renew Cream
A prescription cream for skin changes associated with shifting hormones, with support for hydration, brightness, and resilient-looking skin.
Active ingredients
How Estro-Renew Cream Works
Estro-Renew Cream combines ascorbic acid, estriol, and sodium hyaluronate to support brighter-looking skin, hydration comfort, and hormone-related skin changes when a clinician determines topical estriol is appropriate.
Antioxidant brightening
A vitamin C active used to support brighter-looking skin and antioxidant protection.
Hormonal skin support
A clinician-selected topical option considered for skin changes associated with shifting hormones.
Hydration support
A humectant used to help skin hold water and support a smoother, more comfortable feel.
Formula fit
Is Estro-Renew Cream Right For You?
Not sure whether this hormonal skin formula fits your goals? Take the skin assessment and let a licensed clinician guide your formula match.
- You are noticing skin changes associated with menopause or shifting hormones
- Your goals include hydration, dullness, and resilient-looking skin
- You want clinician-guided topical hormone support when appropriate
- Your clinician determines estriol-based support fits your health history
- You are pregnant, nursing, or trying to conceive
- Your health history makes topical hormone support inappropriate
- You want retinoid-based renewal for texture or fine lines
- Your main concern is acne, redness, or pigmentation rather than hormonal skin changes
Ready to get started?
Ready To Get Started?
- Support for skin changes linked with shifting hormones
- Helps with hydration comfort and brighter-looking skin
- Includes clinician-guided topical estriol when appropriate
- Reviewed and prescribed by a licensed clinician
- Prescription-only treatment
- Ships directly to your door
Additional options
More formulas to compare
Your clinician may consider another prescription option based on your intake, tolerance, and goals.
Pigment Control Cream

- Hydroquinone
A targeted brightening option for persistent dark spots and uneven tone.
- Monthly
- $21.50/mo
- Strength
- 6%
Triple Tone Correcting Cream

- Azelaic Acid
- Niacinamide
- Tranexamic Acid
A multi-active tone option for discoloration, dullness, and melasma-prone concerns.
- Monthly
- $21.50/mo
- Strength
- 10/2/8%
Advanced Spot Correcting Cream

- Hydroquinone
- Kojic Acid
- Tretinoin
A focused correcting cream for stubborn spots and post-blemish marks.
- Monthly
- $21.50/mo
- Strength
- 4/3/0.025%
Questions
What patients ask most
Can I choose this exact formula?
Yes. Add Estro-Renew Cream to your cart to start your short intake. A licensed clinician will review your intake and determine whether this formula is right for you or if there is a better fit.
Can my formula be adjusted?
Yes. If your skin response, tolerance, or goals change, your clinician can recommend a different formula or routine adjustment when appropriate.
How long does it take to see results?
Results vary. Hydration comfort may change sooner for some people, while dullness and overall skin quality usually need consistent use across several weeks or months.
Is this a hormone formula?
Yes. Estro-Renew Cream includes estriol, so a licensed clinician must review your intake and health history before determining whether it is appropriate.
Who should avoid this formula?
Your clinician will decide based on your intake and health history. If you are pregnant, nursing, trying to conceive, or have a history that makes topical hormone support inappropriate, another option may be recommended.
What happens if my skin gets dry or irritated?
Some dryness, stinging, or sensitivity can happen with prescription skincare. Start as directed, moisturize well, use SPF daily, and contact your clinician if irritation becomes uncomfortable or persistent.
Can I change my formula over time?
Yes. Your skin's needs can change, and your treatment plan may change with it. If your skin is too dry, not responding as expected, or your concerns shift, your clinician may adjust your treatment approach or recommend a different formula when appropriate.
Is prescription treatment guaranteed?
No. Prescription treatment is not guaranteed. A licensed clinician will review your intake and determine whether prescription skincare is appropriate for you. If this formula is not the right fit, they may recommend another option or advise a different treatment path.